UPEC Pathway to Chronicity: Bacterial Strain and Host Differences Determine Chronic Outcomes — ASN Events

UPEC Pathway to Chronicity: Bacterial Strain and Host Differences Determine Chronic Outcomes (#223)

Michelle N Chamoun 1 , Matthew J Sullivan 1 , Deepak S Ipe 1 , Mark A Schembri 2 3 , Glen C Ulett 1
  1. School of Medical Science, Menzies health institute Queensland, Griffith Univerisity, Southport, Queensland, Australia
  2. School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia
  3. Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia
Publish consent withheld
  1. Foxman, B., et al., Urinary tract infection: self-reported incidence and associated costs. Annals of Epidemiology, 2000. 10(8): p. 509-15.
  2. Foxman, B., The epidemiology of urinary tract infection. Nature Reviews. Urology, 2010. 7(12): p. 653-60.
  3. Hannan, T.J., et al., Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathogens, 2010. 6(8): p. e1001042.
  4. Schwartz, D.J., et al., Uropathogenic Escherichia coli Superinfection Enhances the Severity of Mouse Bladder Infection. PLoS Pathogens, 2015. 11(1): p. e1004599
  5. O'Brien, V.P., et al., A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease. Nat Microbiol, 2016. 2: p. 16196.
  6. Sivick, K.E., et al., The innate immune response to uropathogenic Escherichia coli involves IL-17A in a murine model of urinary tract infection. Journal of Immunology, 2010. 184(4): p. 2065-75.
#2018ASM